Whole Genome Mapping: A New Paradigm for Sequence Assembly and Genomic Characterization
Tuesday, December 4, 2012 10am to 12pm
About this Event
Central Campus
https://cores.lifesciences.cornell.edu #whole_genome_mapping_a_new_paradigm_for_sequence_assembly_and_genomic_characterizationThe OpGen Argus™ Whole Genome Mapping (WGM) System uses large single molecule reads of 150 Kb to 2.5 Mb to produce de novo high-resolution, ordered restriction maps for strain typing, comparative genomics, and whole-genome sequence assembly of the genomes of microorganisms and larger organisms. WGM facilitates investigation of genetic events such as insertions, deletions, inversions, and copy-number variants (CNVs). OpGen recently announced joint efforts with large whole-genome sequencing institutions like BGI and the Sanger Wellcome Trust Institute, to expand the use of WGM for sequence finishing of human, plant, and animal genomes. The OpGen large genome WGM application uses the long single molecule reads of optical based mapping as well as next generation sequencing data in a hybrid approach to produce “super scaffolds” that significantly improve the overall quality of sequencing projects by increasing N50 scores and decreasing the total number of scaffolds. The large single molecule reads of WGM provide results that second and third generation sequencing technologies alone cannot achieve.
OpGen raffle at the seminar:
Grand Prize – Free Whole Genome Map!
(whole genome map of bacterial sample with ≤6 Mb genome)
This seminar is part of the Life Sciences Advanced Technology Seminar series, sponsored by the Cornell University Life Sciences Core Laboratories Center.
Refreshments will be provided.
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