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Friday, May 31, 2019 at 12:20pm to 1:20pm
Integrated analysis of genotype by environment interaction can reveal the pattern and mechanistic interplay underlying the observed phenotype dynamics. How to uncover patterns at different levels (i.e., population, individual, and gene) to facilitate complex trait dissection and performance prediction is a critical question that needs to be answered. Answers to this question would enhance our ability to conduct genomic and environmental analysis of varied phenotypic plasticity observed in natural field conditions. In this talk, I will describe multiple patterns identified underlying the observed phenotype, and introduce an integrated analytical framework. By revealing the genetic effect continuum and genome-wide marker-effect continua along the environmental gradient, we are proposing a unified synthesis framework to answer questions genome-wide association studies (GWAS), genomic selection (GS), and genotype-by-environmental interaction (G x E). I will relate our ongoing research to the historic debate between the biometrical concept of G x E_b from R. A. Fisher and the developmental concept of G x E_d from Lancelot Hogben, and the “synthetic” work by Clausen-Keck-Hiesey, and the newly proposed “Omnigenic Model” for complex traits.