Weill Institute for Cell and Molecular Biology invites you to the Molecular Cell Bio Group seminar with Patrick J Murphy, Associate Professor in the Department of Molecular Biology and Genetics, Cornell University.

Monday, September 22nd 2025

4:00-5:00 PM - Weill Hall 226

"Transcriptional Priming of Mouse Retrotransposons is Regulated by the Histone Chaperone ANP32E"

The Murphy Lab studies how genes are turned on or off as cells change from one type to another, a process crucial for organismal development and cell identity. Using zebrafish and mouse models, they focus on early developmental stages like gametogenesis, stem cell formation, and differentiation. By combining genetics, developmental biology, DNA sequencing, and bioinformatics, they explore how epigenetic marks—chemical changes that affect gene activity—guide developmental transitions. Their work aims to uncover the molecular mechanisms behind cell state changes, which are important not only for development and reproduction but also for understanding diseases like cancer.

The Molecular Cell Bio Group, hosted by the Weill Institute for Cell and Molecular Biology, is an interdisciplinary meeting to provide opportunities for labs across Cornell’s Ithaca campus to network and share mechanistic biology research and knowledge related broadly to Cell and Molecular Biology. We hope these meetings encourage future collaborations and the sharing of materials and ideas.