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VERSION:2.0
PRODID:icalendar-ruby
CALSCALE:GREGORIAN
X-WR-CALNAME:LASSP SPECIAL SEMINAR
X-WR-TIMEZONE:Eastern Time (US & Canada)
BEGIN:VEVENT
DTSTAMP:20260717T000157Z
UID:tag:localist.com\,2008:EventInstance_999265
DTSTART:20141211T180000Z
DTEND:20141211T190000Z
DESCRIPTION:Dapeng 'Max" Bi\, Department of Physics\, Syracuse University. 
 Professor Eun-Ah Kim\, host.\n\nSeminar Title: Dynamical arrest of cell mo
 tion in tissues: a constant-density rigidity transition\n\nAbstract: For i
 mportant biological functions such as wound healing\, embryonic developmen
 t\, and cancer tumorogenesis\, cells must initially rearrange and move ove
 r relatively large distances\, like a liquid. Subsequently\, these same ti
 ssues must undergo buckling and support shear stresses\, like a solid. Our
  work suggests that biological tissues can accommodate these disparate req
 uirements because the tissues are close to glass or jamming transition. Wh
 ile recent self propelled particle models generically predict a glass/jamm
 ing transition that is driven by packing density φ and happens at some cr
 itical φc < 1\, many confluent biological tissues appear to undergo a jam
 ming transition at a constant density (φ = 1). I will discuss a new theor
 etical framework for predicting energy barriers and rates of cell migratio
 n in 2D tissue monolayers\, and show that this model predicts a novel type
  of jamming transition\, which takes place at constant φ = 1 and depends 
 only on single cell properties such as cell-cell adhesion\, cortical tensi
 on and cell elasticity. I will discuss the implications of these ideas for
  understanding cancer tumor boundaries and metastasis and pattern formatio
 n during development.
GEO:42.449699;-76.481903
LOCATION:Physical Sciences Building\, 416 PSB
SUMMARY:LASSP SPECIAL SEMINAR
URL;VALUE=URI:https://events.cornell.edu/event/lassp_special_seminar_423
CATEGORIES:Seminar
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