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VERSION:2.0
PRODID:icalendar-ruby
CALSCALE:GREGORIAN
X-WR-CALNAME:CCB Seminar Jeff Martell (Univ. of Wisconsin) 
X-WR-TIMEZONE:Eastern Time (US & Canada)
BEGIN:VEVENT
DTSTAMP:20260515T052007Z
UID:tag:localist.com\,2008:EventInstance_48922801235512
DTSTART:20250303T210000Z
DTEND:20250303T220000Z
DESCRIPTION:Title: Merging Abiotic and Biological Catalysis for Sustainable
  Synthesis and Chemical Biology\n\nMy group develops catalysts that merge 
 the benefits of enzymes and abiotic chemistry. In one research area\, we a
 re using DNA as a nano-scaffold to accelerate reactions through pre-organi
 zation of multiple abiotic catalysts\, akin to enzyme active sites but not
  limited to the natural amino acids and cofactors. I will describe our dev
 elopment of a platform to rapidly evaluate millions of DNA nanocatalysts u
 sing DNA barcoding and combinatorial synthesis\, thus mimicking the proces
 s of directed evolution in discovering highly active abiotic catalyst syst
 ems. In our second research area\, we are developing ultrahigh-throughput 
 chemogenetic directed evolution platforms to enhance the activity of natur
 al enzymes in abiotic contexts. I will describe our development of yeast d
 isplay platforms to discover enzyme mutants with improved activity for div
 erse applications\, including recycling of synthetic plastics and proteomi
 c mapping in living cells.
GEO:42.450424;-76.482086
LOCATION:Baker Lab\, 119
SUMMARY:CCB Seminar Jeff Martell (Univ. of Wisconsin) 
URL;VALUE=URI:https://events.cornell.edu/event/ccb-seminar-jeff-martell-uni
 v-of-wisconsin
CATEGORIES:Seminar
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