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X-WR-CALNAME:BME 7900 Seminar: Shana Kelley (Northwestern)
X-WR-TIMEZONE:Eastern Time (US & Canada)
BEGIN:VEVENT
DTSTAMP:20260512T060346Z
UID:tag:localist.com\,2008:EventInstance_51968010058842
DTSTART:20260410T185500Z
DTEND:20260410T201000Z
DESCRIPTION:New Technologies for Measuring and Mapping Inflammation\n\nWe a
 re developing engineering-driven technologies to enable direct\, high-reso
 lution measurement of molecular and cellular activity within human tissues
 . By embedding arrays of microsensors and sampling probes in tissue enviro
 nments\, we aim to continuously monitor biochemical and biophysical signal
 s and define how their perturbation drives inflammation and immune dysregu
 lation. These tissue-integrated platforms are coupled with multi-omics pro
 filing and AI-based analysis to generate comprehensive\, dynamic models of
  inflammatory processes.\n\nOur initial efforts focus on human skin tissue
 \, which provides an accessible and physiologically relevant model to diss
 ect inflammatory dynamics. While advances in genomics and single-cell biol
 ogy have revealed much about the behavior of individual cells\, understand
 ing how billions of cells interact within intact tissues remains a major c
 hallenge. Our integrated platforms are enabling the first holistic and rea
 l-time measurements of immune cell activity within tissue\, allowing us to
  identify molecular tipping points that lead to pathological inflammation.
  Ultimately\, this approach will inform new strategies to predict\, preven
 t\, and control inflammation-driven diseases.\n \n\nBio: Shana Kelley is t
 he President of Bioengineering at Biohub\, Head of Biohub Chicago and the 
 Neena B. Schwartz Professor at Northwestern in the Departments of Chemistr
 y\, Biomedical Engineering\, and Biochemistry & Molecular Genetics. \n\nKe
 lley has pioneered new methods for tracking molecular and cellular analyte
 s with unprecedented sensitivity.  Her work has been recognized with the A
 CS Inorganic Nanoscience Award\, the Pittsburgh Conference Achievement Awa
 rd\, the Steacie Prize\, an Alfred P. Sloan Research Fellowship\, a Camill
 e Dreyfus Teacher-Scholar award\, an NSF CAREER Award\, a Dreyfus New Facu
 lty Award\, and she was also named a “Top 100 Innovator” by MIT’s Te
 chnology Review.  Kelley is also a Guggenheim Fellow\, a Fellow of the Roy
 al Society of Canada\, the Canadian Academy of Health Sciences\, and the A
 merican Institute of Biological and Medical Engineering. She is an elected
  member of the American Academy of Arts and Sciences and the National Acad
 emy of Inventors. Her work is extensively cited\, and she has over 100 pap
 ers cited more than 100 times. \n\nKelley is an inventor on over 50 patent
 s issued worldwide.  She is a founder of five life sciences companies\, Ge
 neOhm Sciences (acquired by Becton Dickinson in 2005)\, Xagenic Inc. (acqu
 ired by General Atomics in 2017)\, CTRL Therapeutics (founded in 2019)\, A
 rma Biosciences (founded in 2021) and Glimmer Therapeutics (founded in 202
 4).
GEO:42.446873;-76.477196
LOCATION:Weill Hall\, 226
SUMMARY:BME 7900 Seminar: Shana Kelley (Northwestern)
URL;VALUE=URI:https://events.cornell.edu/event/bme-7900-seminar-shana-kelle
 y-northwestern
CATEGORIES:Seminar
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