Cornell Center for Antimicrobial Resistance Research & Education Fall Seminar Series 2024

“Surveying the roles of tRNA modification in bacterial pathogenesis”

Adaptation to an antimicrobial environment is critical for the infection of pathogenic bacteria. We focus on the chemical modification of tRNA (tRNA modification) as a potential mechanism underlying bacteria’s adaptation to hostile antimicrobial environments. This seminar will introduce our exploration of tRNA modifications in bacterial pathogens and discuss their roles in environmental adaptation.

Satoshi Kimura Bio:

Dr. Kimura completed his BS, MS, and Ph.D. in Biotechnology at the University of Tokyo, where he learned biochemical approaches and RNA mass spectrometry to study RNA modification under the supervision of Dr. Tsutomu Suzuki. After completion of the short postdoc training at the University of Tokyo, he moved to Boston, Massachusetts, and joined Matthew Waldor's lab at Brigham and Women's Hospital/Harvard Medical School. During his postdoc training, Dr. Kimura developed a high-throughput pipeline to profile tRNA modifications in non-model organisms where tRNA modification is largely unexplored and studied how tRNA modifications modulate tRNA metabolism and function to promote pathogens’ environmental adaptation.