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Tuesday, August 23, 2016 at 12:20pm to 1:45pm
Clark Hall, 700
Central Campus
Guillaume Lambert, Applied and Engineering Physics, Cornell University, Ithaca, NY, will present seminar. Professor Jeffrey Moses, host.
Seminar Title: Quantitative Single-Cell Biophysics: Unraveling Bacterial Adaptation Dynamics under Fluctuating Environments
Abstract: Our research is motivated by the notion that complex behaviors in bacteria (e.g. pathogenicity, antibiotic resistance, gene regulation and cell-fate decisions, etc.) often arise from cell-to-cell variability within members of a population. Consequently, to gain sufficient insight into active biological processes, information about microorganisms must be gathered at the single-cell level and in real time. To this end, we combine tools from Physics, Bioengineering, and Synthetic Biology to monitor the response of individual bacteria subjected to environmental fluctuations. We believe that the study of naturally-occurring regulatory systems can lead to the discovery of physical and biological principles broadly applicable to the development of biomedical and diagnostics applications. Ongoing research projects that will be discussed in this talk include: 1) the study of the survival strategies used by bacteria in response to toxic environments, 2) a quantitative description of a biological clock and its robustness to perturbations, and 3) the development of a rapid, low-cost diagnostic platform for infectious diseases.
Mr. Douglas E. Milton, Sr.
607-255-9684
Guillaume Lambert
Cornell University
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