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Tuesday, April 30, 2019 at 12:20pm to 1:15pm
700 Clark Hall
Title: Single-molecule Approaches in Mechanobiology: From DNA nanoswitches to the Centrifuge Force Microscope
Abstract:
Mechanical force plays a critical role in regulating many aspects of biological function and structure, particularly at the nanoscale. My research group develops and applies methods in single-molecule manipulation to understand the force-dependent dynamics of biological interactions. I will present some methods that we are developing, including massively parallel single-molecule force measurements using centrifugal force, and nanoscale devices built using DNA origami, and demonstrate how these approaches can bring new insights into biological processes such as blood clotting and hearing.
Hosted by Itai Cohen
Lea Reagan
607-255-9684
Wesley Wong
Harvard
https://wyss.harvard.edu/team/associate-faculty/wesley-wong/
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