Biophysics Colloquium with Adam Hall

Wednesday, March 1, 2017 at 4:00pm to 5:00pm

Clark Hall, 700
Central Campus

Adam Hall, Virginia Tech - Wake Forest

Host: Iwijn De Vlaminck

Novel detection strategies for disease biomarkers using nanotechnology

Nanoscale devices have long held potential for disease diagnostics due to their inherent scale and sensitivity, but challenges in implementation, reproducibility, and cost have hampered progress. In our lab, we are working to address these challenges by improving both the production of and the applications for the emerging platform of solid-state nanopores. I will first discuss our advanced fabrication tools for making nanopore devices with precision, speed, and flexibility, and then I will present two novel assays we have developed using the resulting system. With the first, we are able to detect nucleic acid biomarkers that include epigenetic modifications and specific sequences with relevance to fields that include oncology and infectious diseases. With the second, we are able to assess native hydrophobic proteins that play a role in pathologies like Celiac’s disease.

[cid:A0590249-0F21-43A3-B548-B6F0E0EA16BA]

poster

Event Type

Seminar

Departments

LASSP

Tags

biophysics, biophysics_colloquium, lassp

Contact E-Mail

jdf55@cornell.edu

Contact Name

Jonathan Fuller

Contact Phone

255-8101

Speaker

Adam Hall

Speaker Affiliation

Virginia Tech - Wake Forest School

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